We have co-initiated and are co-leading a multi-year project in South Africa to help improve quality and quantity of care for the increasing numbers of orphaned and vulnerable children.In November 2007 we ran the first “Innovation Lab” with 60 key national leaders working in this field from government, civil society, business, academic and medical institutions, and donor organisations. This was the launch event of an ongoing leadership and innovation network working to build collaboration, leadership, systemic approaches, and innovation in this field.